Variants in the WDR44 WD40-Repeat Domain Cause a Spectrum of Ciliopathy by Impairing Ciliogenesis Initiation
Submitted by rnd_admin on Sun, 11/03/2024 - 19:31
Prof. Sung-Gyoo Park and Jong-Hee Chae
Professor Sung-Gyoo Park's research team from the College of Pharmacy at SNU has discovered WDR44 variants that induce human ciliopathy through international collaborative work with researchers from 8 nations. Park’s team found that WDR44 is a new member of ciliopathy-related genes by holding Rab11, a downstream protein, to prevent ciliogenesis.
2024. 1. 18.